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Alli ( Xenical) what you need to know

Alli (pronounced AL-eye) is an over-the-counter weight-loss medication for overweight adults who are having trouble losing weight. Is Alli your weight-loss solution, with its simple access and weight-loss promises?

What exactly is Alli?

Alli is a 60-milligram over-the-counter variant of the prescription medication orlistat (Xenical). Both Alli and Xenical are supposed to be used in conjunction with a low-calorie, low-fat diet and regular physical activity to help you lose weight.

Adults 18 and older with a body mass index (BMI) of 25 or more are eligible to use Alli. Adults with a BMI of 30 or more (obesity) and those with a BMI of 27 to 29 (overweight) who have other health risk factors such as high blood pressure or diabetes are eligible to take Xenical.

Is orlistat a cause for concern?

because of rare reports of serious liver injury in persons taking orlistat, the Food and Drug Administration (FDA) published a safety evaluation in 2010. Orlistat was not found to be the cause of the reported liver damage, according to the FDA.However, as a result of the reports, the labels for Alli and Xenical were changed. If you see any of the following signs or symptoms, consult your doctor right away:


Appetite loss.

Eyes or skin that is yellow

Stool in a light color

Urine color is brown.

What is Alli's method of operation?

Orlistat (the key ingredient in Alli) helps you lose weight by lowering the amount of fat you absorb in your intestines.

Lipase is a digestive enzyme that aids in the breakdown of dietary fat into smaller components so that it can be consumed or stored for energy. Lipase is inhibited by orlistat. About 25% of the fat you consume is not broken down and is removed through bowel movements when you take the medicine with a meal.

How much weight could Alli help me lose?

Alli may aid weight reduction, but it will most likely be minor — perhaps a few pounds more than you would lose with food and exercise alone.

Within a year, more than 40% of patients who took Alli and followed a calorie-restricted diet and increased physical activity lost 5% or more of their body weight. Clinically relevant weight loss is defined as losing 5% or more of one's body weight to begin lowering the risk of cardiovascular disease, diabetes, and other diseases.

People who followed a calorie-restricted diet, exercised consistently, and took Alli lost 5.7 pounds (2.6 kilograms) more in a year than those who only dieted and exercised.

What is Alli's disposition?

Up to three times a day, one 60-milligram Alli pill is taken within an hour following a fat-containing meal. Fat consumption should be spread out among the three main meals and should not exceed 30% of total calories. A fat intake of roughly 15 grams per meal is recommended by the manufacturer.

You don't need a dose of Alli if you consume a meal that is fat-free. You'll probably have more severe gastrointestinal side effects if you take Alli with a high-fat meal.

Alli can impair fat-soluble nutrient absorption, such as beta carotene and vitamins A, D, E, and K. Take a multivitamin before going to bed and at least two hours after your previous Alli dose.

Is there a list of Alli's side effects?

Orlistat, the key ingredient in Alli, causes gastrointestinal side effects due to the passage of undigested lipids through your digestive tract. They usually fade away with time and proper medicine administration. These are some of the negative effects:

Discomfort or pain in the abdomen

The anus produces an oily discharge.

Anal discharge with greasy gas

Stools that are oily

Having more bowel motions

Bowel movements that are urgent or difficult to control

The following are some more probable adverse effects:


Back ache

Infection of the upper respiratory tract

When should you avoid taking Alli?

Before you start taking Alli, talk to your doctor about possible drug interactions, especially if you're taking medication for any of the following conditions:


Thyroid illness is a condition that affects the thyroid gland

Irregular heartbeat is a condition in which the heartbeat is irregular.

Cardiovascular disease (CVD) is a condition that affect



It's also a good idea to tell your doctor if you've had:

Problems with the gallbladder

Stones in the kidneys


Irritable bowel syndrome (IBS) is a type of irritable bowel syndrome

If you're looking for a way to lose weight, Alli isn't for you. if you have these problems

Are you at a good weight?

Have you undergone an organ transplant?

Do you take cyclosporine? (Neoral, Sandimmune, others)

Have you been having trouble absorbing food?

Are you pregnant or nursing a child?

How long should I take Alli?

If you lose roughly 1 pound (0.5 kilogram) each week during the first month and have lost 5% or more of your pre-treatment body weight after one year, your weight-loss plan with diet, exercise, and pharmacological therapy is deemed successful.

If the treatment is successful, sticking to the diet, exercise, and drug treatment plan will help you keep the weight off or lose more.

The medicine causes the majority of weight reduction in the first few months. Continuing the medicine may be of little value if you have followed the diet and activity regimen and have not dropped at least 5% of your initial body weight within a few months.

If you haven't dropped 5% of your body weight after a year on the regimen, it's a good idea to stop taking the medicine. The medication's dangers, side effects, and cost are likely to outweigh any potential benefits.

What role does Alli play in a healthy weight-loss strategy?

Alli isn't a quick fix for weight loss. It takes a commitment to consume a balanced diet and engage in regular physical activity to lose weight and keep it off.

Consult your doctor to examine the benefits and hazards of Alli or any other weight-loss medication. You and your doctor can work together to develop the best weight-loss plan for you.